Dupuytren Disease and Related Diseases - The Cutting Edge

Author: Paul M. N. Werker,Joseph Dias,Charles Eaton,Bert Reichert,Wolfgang Wach

Publisher: Springer

ISBN: 3319321994

Category: Medical

Page: 450

View: 8644

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In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase injection, percutaneous needle fasciotomy, and other surgical and minimally invasive approaches is then extensively discussed. Comparative studies of different approaches are reviewed, and aspects of patient assessment, examined. The prevention and treatment of disease recurrences are also addressed. Further sections consider related conditions, other treatment options, and future pathways for research. This book should be read by all who treat or conduct research into Dupuytren disease. It is based on presentations delivered at the 2015 International Conference on Dupuytren Disease, held in Groningen, the Netherlands, which was designed to promote a coordinated global response to the disease involving patients, scientists, and clinicians.

Collagenase in Dupuytren Disease

Author: Giorgio Pajardi,Marie A. Badalamente,Lawrence C. Hurst

Publisher: Springer

ISBN: 3319658220

Category: Medical

Page: 142

View: 1743

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This book offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren’s contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotomy, and lipofilling. Clear guidance is provided on technique, current indications, and off-label usage. With the help of tips and tricks from leading experts, the reader will learn how to personalize the procedure to meet the needs of individual patients. Advice is also provided on all aspects of rehabilitation, which is a key determinant of treatment outcome. Collagenase treatment of Dupuytren’s disease has the benefits of low invasiveness and rapid patient recovery and achieves reasonable recurrence-free periods. It is especially valuable in patients with rapid recurrence following surgery. In documenting and appraising every aspect of its use, this book will be of value for all who treat patients with Dupuytren’s disease, including hand surgeons, orthopedists, plastic surgeons, physiatrists, and physiotherapists.

Dupuytren Disease, An Issue of Hand Clinics E-Book

Author: Steven Haase,Kevin C. Chung

Publisher: Elsevier Health Sciences

ISBN: 0323613896

Category: Medical

Page: N.A

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This issue of Hand Clinics, guest edited by Dr. Steve Haase, as well as the series’ consulting editor Dr. Kevin Chung, will cover a number of key aspects of Dupuytren Disease. Topics discussed within the issue include, but are not limited to: Risk Factors, Disease Associations, and Dupuytren Diathesis, Pathologic Anatomy in Dupuytren Disease, Needle Aponeurotomy for Dupuytren Disease, Development of Collagenase Treatment for Dupuytren Disease, Collagenase Injection for Dupuytren Disease, Alternative and Adjunctive Treatments for Dupuytren Disease, Comparative Outcomes of Dupuytren Disease Treatment, Complications of Dupuytren Disease Treatment, The Role of Hand Therapy in Dupuytren Disease, Treatment of Recurrent Dupuytren Disease, and Advances in Minimally Invasive Treatment of Dupuytren Disease.

Radiation and the Immune System: Current Knowledge and Future Perspectives

Author: Katalin Lumniczky,Serge M. Candéias,Udo S. Gaipl,Benjamin Frey

Publisher: Frontiers Media SA

ISBN: 2889454746

Category:

Page: N.A

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For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.

Dupuytren’s Disease and Related Hyperproliferative Disorders

Principles, Research, and Clinical Perspectives

Author: Charles Eaton,M. Heinrich Seegenschmiedt,Ardeshir Bayat,Giulio Gabbiani,Paul Werker,Wolfgang Wach

Publisher: Springer Science & Business Media

ISBN: 3642226973

Category: Medical

Page: 474

View: 6164

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This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder.


Essential Surgery

Problems, Diagnosis and Management With STUDENT CONSULT Online Access

Author: Clive R. G. Quick,Joanna B Reed,Simon J.F. Harper,Kourosh Saeb-Parsy,Philip J. Deakin

Publisher: Elsevier Health Sciences

ISBN: 0702054836

Category: Medical

Page: 720

View: 5664

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Essential Surgery is a comprehensive and highly illustrated textbook suitable for both clinical medical students as well junior surgical trainees, preparing for postgraduate qualifications in surgery such as the MRCS. Covering general surgery, trauma, orthopaedics, vascular surgery, paediatric surgery, cardiothoracic surgery and urology, it incorporates appropriate levels of basic science throughout. The book is ideal for modern clinical courses as well as being a practical manual for readers at more advanced levels. Its main aim is to stimulate the reader to a greater enjoyment and understanding of the practice of surgery. Essential Surgery incorporates a problem-solving approach wherever possible, emphasising how diagnoses are made and why particular treatments are used. The pathophysiological basis of surgical diseases is discussed in relation to their management, acting as a bridge between basic medical sciences and clinical problems. The uniformity of the writing style and the clarity of elucidation will encourage continued reading, while the emphasis on the principles of surgery will enable a real understanding of the subject matter. The book’s extensive use of original illustrations, boxes and tables emphasises important concepts and will aid revision. The principles of operative surgery and perioperative care are explained together with outlines of common operations, enabling students and trainee surgeons to properly understand procedures and to participate intelligently in the operating department. A major revision of the text has taken full account of the progressive evolution of surgery and includes new concepts that have advanced medical understanding. New topics have been added to ensure the book’s contents match the curriculum of the UK Intercollegiate MRCS examination, including patient safety, surgical ethics, communication, consent, clinical audit and principles of research. The broad experience of surgical teaching and training of two new authors has brought a fresh perspective on the book’s contents and its presentation. New consensus guidelines for managing common disorders have been incorporated where appropriate.

Crash Course: Surgery E-Book

Author: Angeliki Kontoyannis,Helen Sweetland

Publisher: Elsevier Health Sciences

ISBN: 0723437122

Category: Medical

Page: 358

View: 7373

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Covering all aspects of the syllabus, Crash Course offers students a fast way to recap on what they need to know to get through the exams with ease. Styled in an easy-to-follow, readily accessible format, each book is prepared by senior medical students or junior doctors - under faculty supervision - to give them the correct level of information perfectly tailored to current curricula requirements. The series now includes improved pedagogic features and a fully revised self-assessment section, updated to meet current examination needs. Provides the exam syllabus in one place! Written by senior medical students or junior doctors – authors WHO REALLY UNDERSTAND today’s exam situation! Senior Faculty Advisors ensure complete accuracy of the text! Full artwork programme, improved ‘Hints and Tips’ boxes, and ‘Communication’ boxes help you remember the key points! Self-Assessment section – fully updated to reflect new curriculum requirements – helps you maximise your grade! Solid, accurate, user-friendly coverage provides enough detail even for those aiming at distinction! Fully updated self-assessment section – ideal for current examination practice! Includes useful ‘Learning Objectives’ at the start of each chapter Pharmacological and disease management information updated in line with current best practice guidelines Includes recent research findings Discusses key aspects of patient communication – presented in easy ‘Communication’ boxes Fully updated to include feedback from hundreds of students! Welcome to Crash Course – THE revision aid to get you the results you need!! Crash Course is a complete revision guide designed specifically to save you time by providing everything you could be asked in the exam in one place! Each book in the series has been specially written either by senior medical students or junior doctors – carefully supervised by faculty advisors – to ensure that it exactly matches your needs by having been prepared by someone who has just been in the exam situation! Fully updated with improved layout, the first part of each volume covers a comprehensive series of common presentations while the second part addresses specific diseases and disorders. The third part of the book is given to a detailed exploration of the role of history, examination, and common investigations in the relevant speciality providing all of the facts you need to get things right! New features include ‘Learning Objectives’ at the start of each chapter, improved ‘Hints and Tips’ boxes, ‘Communication’ boxes and a completely revised self-assessment section tailored to the current exam formats! Crash Course – an easier way to get through the exam!

Mediale Medizin

Der wahre Ursprung von Krankheit und Heilung

Author: Anthony William

Publisher: Arkana

ISBN: 3641183901

Category: Body, Mind & Spirit

Page: 464

View: 1848

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Seit seiner Kindheit besitzt Anthony William eine einzigartige Gabe: Ein göttlicher Geist flüstert ihm äußerst präzise Informationen zum Gesundheitszustand seiner Mitmenschen ins Ohr. Diese medialen Botschaften zeigen nicht nur, an welcher Krankheit der Betroffene leidet, sondern auch, wie er wieder vollständig gesund wird – und sind dem heutigen Stand der Medizin oft um Lichtjahre voraus. Dieses Buch enthält erstmals das revolutionäre Heilwissen, das sich Anthony William in seiner langjährigen, erfolgreichen Praxis als medizinisches Medium erwarb. Es zeigt die wahren Ursachen von Krankheiten, die in der Medizinwissenschaft als chronisch oder unheilbar gelten, wie beispielsweise Rheumatoide Arthritis, Multiple Sklerose, Typ-2-Diabetes, hormonelle Erkrankungen, chronisches Müdigkeitssyndrom oder Borreliose. Neben der Ursache benennt William einfache, leicht gangbare Wege der Heilung: Detox, Superfoods, Ernährungstipps und eine reinigende 28-tägige Heilkur.

Kumar and Clark's Clinical Medicine E-Book

Author: Parveen Kumar,Michael L Clark

Publisher: Elsevier Health Sciences

ISBN: 070205304X

Category: Medical

Page: 1352

View: 5826

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Kumar & Clark’s Clinical Medicine 8 builds on the prize-winning formula that won the first prize in the BMA Book Awards Medicine Category in 2010 (7th edition) and 2006 (6th edition). ‘This book is comprehensive, student friendly (if still intimidating in size!) and covers such a vast breadth of knowledge. It still remains the primary ‘must-have’ text book of any budding doctor, or qualified one at that. This book is stunning in its breadth and in its ease of use. It still remains as the ‘gold-standard’ thorough guide to clinical medicine its forefathers were.’ BMA Judges 2010 'This is one of a select few books that deserves to be in most doctors' personal possession and it's as simple as that. ...’ Dr Harry Brown. New to this edition: New chapter on palliative medicine. Five times the number of margin clinical photos. New echocardiography images. Double the number of dermatological images; including all the major lesion morphologies covered in a single page. 16 new authors. New sections on protein synthesis, energy production and stem cells. New members of the International Advisory Board from India, South Africa, Poland and the Middle East. 7 new online chapters from the International Advisory Board. Key online features: 30 extra short chapters online, written by members of the International Advisory Board to cover key international issues, such as malaria, envenoming and HIV. Animated practical procedures, including lumbar puncture, central venous and bladder catheterization, arterial cannulation etc. heart and lung sounds, and interactive surface anatomy available online. Full text online through StudentConsult. Add your own notes and bookmarks. Search across all the StudentConsult resources you own online in one place. New to this edition: New chapter on palliative medicine. Five times the number of margin clinical photos. New echocardiography images. Double the number of dermatological images; including all the major lesion morphologies covered in a single page. 16 new authors. New sections on protein synthesis, energy production and stem cells. New members of the International Advisory Board from India, South Africa, Poland and the Middle East. 7 new online chapters from the International Advisory Board.


Rehabilitation of the Hand and Upper Extremity, 2-Volume Set E-Book

Expert Consult

Author: Terri M. Skirven,A. Lee Osterman,Jane Fedorczyk,Peter C. Amadio

Publisher: Elsevier Health Sciences

ISBN: 0323081266

Category: Medical

Page: 2096

View: 821

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With the combined expertise of leading hand surgeons and therapists, Rehabilitation of the Hand and Upper Extremity, 6th Edition, by Drs. Skirven, Osterman, Fedorczyk and Amadio, helps you apply the best practices in the rehabilitation of hand, wrist, elbow, arm and shoulder problems, so you can help your patients achieve the highest level of function possible. This popular, unparalleled text has been updated with 30 new chapters that include the latest information on arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management. An expanded editorial team and an even more geographically diverse set of contributors provide you with a fresh, authoritative, and truly global perspective while new full-color images and photos provide unmatched visual guidance. Access the complete contents online at www.expertconsult.com along with streaming video of surgical and rehabilitation techniques, links to Pub Med, and more. Provide the best patient care and optimal outcomes with trusted guidance from this multidisciplinary, comprehensive resource covering the entire upper extremity, now with increased coverage of wrist and elbow problems. Apply the latest treatments, rehabilitation protocols, and expertise of leading surgeons and therapists to help your patients regain maximum movement after traumatic injuries or to improve limited functionality caused by chronic or acquired conditions. Effectively implement the newest techniques detailed in new and updated chapters on a variety of sports-specific and other acquired injuries, and chronic disorders. Keep up with the latest advances in arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management See conditions and treatments as they appear in practice thanks to detailed, full-color design, illustrations, and photographs. Access the full contents online with streaming video of surgical and rehabilitation techniques, downloadable patient handouts, links to Pub Med, and regular updates at www.expertconsult.com. Get a fresh perspective from seven new section editors, as well as an even more geographically diverse set of contributors.


Manual of Ambulatory Surgery

Author: K.J. Kassity,J.E. McKittrick,F.W. Preston

Publisher: Springer Science & Business Media

ISBN: 146125731X

Category: Medical

Page: 266

View: 7304

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The first hospital-affiliated surgical unit designed specifically for ambulatory surgery in the state of California began functioning as part of Santa Barbara Cottage Hospital in 1973. As this text is readied for publication, the unit is in its tenth year of operation. More than 20,000 patients have undergone surgery there. The enthusiasm generated by ~\ir experience in Santa Barbara, along with the widespread, growing interest in ambulatory surgery, prompted us to undertake this volume. The first three chapters cover principles and administrative aspects, an esthesiology, and nursing in the ambulatory surgical center. Subsequent chap ters, the major portion of the text, provide detailed, meticulously illustrated descriptions of surgical procedures as they are done in the Santa Barbara Cottage Hospital Outpatient Surgical Center by the surgeons who work there. They reflect current practice and emphasize the techniques found most reliable by the surgeons who use them in the outpatient setting. This manual includes many of the operations most commonly performed in our facility and emphasizes the unique aspects of surgery and patient care in outpatient practice. The text is concise, practical, and based on our collective experience. The illustrations are, for the most part, drawn from the surgeon's perspective and faithfully render the actual appearance of the operative field during surgery. Supplementary cross-sectional and conceptual drawings are included to orient the reader.

Dupuytren's Disease

Biology and Treatment

Author: Robert M. McFarlane,D. A. McGrouther

Publisher: N.A

ISBN: N.A

Category: Medical

Page: 451

View: 4231

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A dictionary of practical surgery

comprehending all the most interesting improvements from the earliest times down to the present period : an account of the instruments and remedies employed in surgery : the etymology and signification of the principal terms : and, numerous references to ancient and modern works forming a catalogue of surgical literature arranged according to subject

Author: Samuel Cooper,David Meredith Reese

Publisher: N.A

ISBN: N.A

Category: Medical

Page: 1165

View: 1106

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Surgery

Author: James O. Robinson,Ashley Brown

Publisher: N.A

ISBN: 9780433281047

Category: Medical

Page: 604

View: 9365

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Das andere Geschlecht

Sitte und Sexus der Frau

Author: Simone de Beauvoir

Publisher: Rowohlt Verlag GmbH

ISBN: 3644051615

Category: Social Science

Page: 944

View: 9090

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Das berühmte Standardwerk von Simone de Beauvoir. Die universelle Standortbestimmung der Frau, die aus jahrtausendealter Abhängigkeit von männlicher Vorherrschaft ausgebrochen ist, hat nichts an Gültigkeit eingebüßt. Die Scharfsichtigkeit der grundlegenden Analyse tritt in der Neuübersetzung noch deutlicher hervor.

Neue Techniken Fußchirurgie

Author: Hajo Thermann

Publisher: Springer-Verlag

ISBN: 3662527375

Category: Medical

Page: 139

View: 2072

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In diesem Buch, das nun in der komplett neu strukturierten und erweiterten 2. Auflage vorliegt, werden zahlreiche neue und aktuelle operative Techniken rund um den Fuß umfassend dargestellt. Seit Jahren ist der Autor in seinem Fachgebiet hoch spezialisiert. Mit den vorgestellten Operationsverfahren regt er erneut zur Diskussion und zur Kommunikation an. Alle Operationen werden mit brillanten Grafiken step-by-step visualisiert und kurze, präzise Texte beschreiben darüber hinaus das operative Vorgehen. So ist die Umsetzung der Theorie in die Praxis problemlos möglich!