Dupuytren Disease and Related Diseases - The Cutting Edge

Author: Paul Werker,Joseph Dias,Charles Eaton,Bert Reichert,Wolfgang Wach

Publisher: Springer

ISBN: 3319321994

Category: Medical

Page: 450

View: 7548

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In this book, leading international experts showcase the latest advances in research into Dupuytren disease and its clinical management. The coverage spans all relevant specialties, including cell biology, biomechanics, genomics, surgery, pharmacotherapy, and radiotherapy. The opening sections address epidemiology, cellular and extracellular events, and genetics. Treatment by means of collagenase injection, percutaneous needle fasciotomy, and other surgical and minimally invasive approaches is then extensively discussed. Comparative studies of different approaches are reviewed, and aspects of patient assessment, examined. The prevention and treatment of disease recurrences are also addressed. Further sections consider related conditions, other treatment options, and future pathways for research. This book should be read by all who treat or conduct research into Dupuytren disease. It is based on presentations delivered at the 2015 International Conference on Dupuytren Disease, held in Groningen, the Netherlands, which was designed to promote a coordinated global response to the disease involving patients, scientists, and clinicians.

Collagenase in Dupuytren Disease

Author: Giorgio Pajardi,Marie A. Badalamente,Lawrence C. Hurst

Publisher: Springer

ISBN: 3319658220

Category: Medical

Page: 142

View: 7721

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This book offers detailed guidance on the use of collagenase, or enzymatic fasciotomy, as a nonsurgical treatment for Dupuytren’s contracture and explains its role in relation to the other forms of treatment, including open fasciectomy, needle aponeurotomy, and lipofilling. Clear guidance is provided on technique, current indications, and off-label usage. With the help of tips and tricks from leading experts, the reader will learn how to personalize the procedure to meet the needs of individual patients. Advice is also provided on all aspects of rehabilitation, which is a key determinant of treatment outcome. Collagenase treatment of Dupuytren’s disease has the benefits of low invasiveness and rapid patient recovery and achieves reasonable recurrence-free periods. It is especially valuable in patients with rapid recurrence following surgery. In documenting and appraising every aspect of its use, this book will be of value for all who treat patients with Dupuytren’s disease, including hand surgeons, orthopedists, plastic surgeons, physiatrists, and physiotherapists.

Dupuytren Disease, An Issue of Hand Clinics E-Book

Author: Steven Haase,Kevin C. Chung

Publisher: Elsevier Health Sciences

ISBN: 0323613896

Category: Medical

Page: N.A

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This issue of Hand Clinics, guest edited by Dr. Steve Haase, as well as the series’ consulting editor Dr. Kevin Chung, will cover a number of key aspects of Dupuytren Disease. Topics discussed within the issue include, but are not limited to: Risk Factors, Disease Associations, and Dupuytren Diathesis, Pathologic Anatomy in Dupuytren Disease, Needle Aponeurotomy for Dupuytren Disease, Development of Collagenase Treatment for Dupuytren Disease, Collagenase Injection for Dupuytren Disease, Alternative and Adjunctive Treatments for Dupuytren Disease, Comparative Outcomes of Dupuytren Disease Treatment, Complications of Dupuytren Disease Treatment, The Role of Hand Therapy in Dupuytren Disease, Treatment of Recurrent Dupuytren Disease, and Advances in Minimally Invasive Treatment of Dupuytren Disease.

Radiation and the Immune System: Current Knowledge and Future Perspectives

Author: Katalin Lumniczky,Serge M. Candéias,Udo S. Gaipl,Benjamin Frey

Publisher: Frontiers Media SA

ISBN: 2889454746

Category:

Page: N.A

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For long, high dose ionizing radiation was considered as a net immune suppressing agent, as shown, among others, by the exquisite radiosensitivity of the lymphoid system to radiation-induced cell killing. However, recent advances in radiobiology and immunology have made this picture more complex. For example, the recognition that radiation-induced bystander effects, share common mediators with various immunological signalling processes, suggests that they are at least partly immune mediated. Another milestone was the finding, in the field of onco-immunology, that local tumor irradiation can modulate the immunogenicity of tumor cells and the anti-tumor immune responsiveness both locally, in the tumor microenvironment, and at systemic level. These observations paved the way for studies exploring optimal combinations of radiotherapy and immunotherapy in order to achieve a synergistic effect to eradicate tumors. However, not all interactions between radiation and the immune system are beneficial, as it was recognized that many of radiation-induced late side effects are also of immune and inflammatory nature. Currently perhaps the most studied field of research in radiation biology is focused around the biological effects of low doses, where many of the observed pathophysiological endpoints are due to mechanisms other than direct radiation-induced cell killing and are immune-related. Finally, it must not be forgotten that the interactions between the ionizing radiations and the immune system are bi-directional, and activation of the immune system also influences the outcome of radiation exposure. This Research Topic brings together 23 articles and aims to give an overview of the complex and very often contradictory nature of the interactions between ionizing radiation and the immune system. Due to its increasing penetrance in the population both through medical diagnostic or environmental sources or during cosmic travel low dose ionizing radiation exposure is becoming a major epidemiological concern world-wide. Several of the articles within the Research Topic specifically address potential long-term health consequences and the underlying mechanisms of low dose radiation exposure. A major intention of the Editors was also to draw the attention of the non-radiobiological scientific community on the fact that ionizing radiation is by far more than purely an immune suppressing agent.

Dupuytren’s Disease and Related Hyperproliferative Disorders

Principles, Research, and Clinical Perspectives

Author: Charles Eaton,M. Heinrich Seegenschmiedt,Ardeshir Bayat,Giulio Gabbiani,Paul M. N. Werker,Wolfgang Wach

Publisher: Springer Science & Business Media

ISBN: 3642226965

Category: Medical

Page: 474

View: 1739

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This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder.

Dupuytren’s Disease and Related Hyperproliferative Disorders

Principles, Research, and Clinical Perspectives

Author: Charles Eaton,M. Heinrich Seegenschmiedt,Ardeshir Bayat,Giulio Gabbiani,Paul Werker,Wolfgang Wach

Publisher: Springer Science & Business Media

ISBN: 3642226973

Category: Medical

Page: 474

View: 5133

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This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder.

Dupuytren’s Disease

A Concept of Surgical Treatment

Author: Peter Brenner,Ghazi M. Rayan

Publisher: Springer Science & Business Media

ISBN: 3709160618

Category: Medical

Page: 241

View: 7587

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Morbus Dupuytren is particularly widespread among northern Europeans. However, the therapeutic success-rate often leaves much to be desired. A 50% recurrence-rate after surgery indicates that the disease cannot be treated by surgery alone. This book therefore adopts two parallel approaches: emphasis is firstly placed on the systemic character of morbus Dupuytren in context with other connective tissue diseases by a description of the biochemical and molecular-biological changes in the diseased connective tissues; secondly, a diversified picture of the given anatomical facts serves to explain the employment of the various therapeutic approaches. Further, a description is given of the current surgical procedures.

The Shoulder

Author: Gazi Huri,Nikolaos K. Paschos

Publisher: Springer

ISBN: 3319519794

Category: Medical

Page: 453

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This book provides a broad overview of operative and non-operative treatments of various conditions affecting the shoulder. It is presented in an easy to use format with each chapter including multiple choice questions to assist the reader in preparing for boards to improve shoulder knowledge and increase success in exams. The Shoulder clearly describes the basic science, anatomy, biomechanical features and principals of physical examination while utilising an algorithmic approach to shoulder disorders. The contributors are an international team of shoulder experts who understand what is important to know at every level. The result is a book of value to those new to shoulder challenges and also experienced surgeons who wish to have a quick and handy guide to current concepts and knowledge of shoulder conditions and treatment.

New Techniques in Foot and Ankle Surgery

Author: Hajo Thermann

Publisher: Springer

ISBN: 3319596748

Category: Medical

Page: 156

View: 9961

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This book presents in exquisite detail numerous new surgical techniques for the treatment of foot and ankle conditions, as well as the latest refinements of established procedures. All operations are depicted step by step with the aid of superb illustrations, with precise and succinct accompanying descriptions. The author is an expert in the field, with many years of experience, whose goals here are to facilitate the smooth translation of theory into practice and to stimulate further discussions and communications regarding optimal surgical management. The book is already in its second edition in German. Among the key features of this first English edition are the latest advances in arthroscopy, surgical procedures on the Achilles tendon, interventions for treatment of lateral ligament and syndesmotic ankle injuries, surgical interventions on the metatarsophalangeal joint, surgical correction of hindfoot deformities, forefoot surgery, and ankle arthroplasty. The book will be of value for foot and ankle surgeons at all levels.

Minimally Invasive Surgery in Orthopedics

Author: Giles R. Scuderi,Alfred J. Tria

Publisher: Springer Science & Business Media

ISBN: 9780387766089

Category: Medical

Page: 694

View: 4827

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Minimally invasive surgery has evolved as an alternative to the traditional approaches in orthopedic surgery and has gathered a great deal of attention. Many surgeons are now p- forming all types of procedures through smaller surgical felds. Along with changes in the surgical technique, there have been rapid advances in computer navigation and robotics as tools to enhance the surgeon’s vision in the limited operative felds. With these new techniques and technologies, we must ensure that these procedures are performed safely and effectively with predictable clinical outcomes. This book has been expanded from our previous publi- tions to include spine and foot and ankle surgery, along with updated sections on knee arth- plasty, hip arthroplasty, and upper extremity surgery. The clinical information and surgical techniques, along with tips and pearls, provided by experts in the feld allows the reader to grasp a comprehensive understanding of the nuances of MIS. It is our intention that this text will be a valuable reference for all orthopedic surgeons. New York, NY Giles R. Scuderi, MD Piscataway, NJ Alfred J. Tria, MD v BookID 127440_ChapID FM_Proof# 1 - 14/09/2009 Contents Section I The Upper Extremities 1 What Is Minimally Invasive Surgery and How Do You Learn It? . . . . . . . . . . . . . . . . . . . . . 3 Aaron G. Rosenberg 2 Overview of Shoulder Approaches: Choosing Between Mini-incision and Arthroscopic Techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Raymond A. Klug, Bradford O. Parsons, and Evan L. Flatow 3 Mini-incision Bankart Repair . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Edward W. Lee, Kenneth Accousti, and Evan L. Flatow 4 Mini-open Rotator Cuff Repair . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Complications in Foot and Ankle Surgery

Management Strategies

Author: Michael S. Lee,Jordan P. Grossman

Publisher: Springer

ISBN: 3319536869

Category: Medical

Page: 452

View: 2872

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Comprehensive, current and insightful, this well-illustrated text is devoted to the detailed management of common but often challenging complications that all foot and ankle surgeons encounter in their practice. Opening with a discussion of the "anatomy" of a complication, the book is divided into five thematic sections - perioperative, forefoot, first ray, midfoot/hindfoot and ankle - with each chapter detailing the development and evolution of both major and minor complications, the evaluation and decision-making involved, and the best surgical management techniques for each. Perioperative topics covered include surgical infection, venous thromboembolism, and incisional complications, with the subsequent sections detailing complications following specific conditions, such as hallux valgus, calcaneal fractures, and the Charcot foot, among many others. Boasting a diverse and experienced authorship and Editors who are past Presidents of the American College of Foot and Ankle Surgeons, Complications in Foot and Ankle Surgery is a unique and timely resource for foot and ankle surgeons worldwide who treat these challenging conditions.

Essentials of Hand Surgery

Author: John Gray Seiler

Publisher: Lippincott Williams & Wilkins

ISBN: 9780781735858

Category: Medical

Page: 276

View: 639

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Essentials of Hand Surgery is a complete, authoritative, practical guide to the evaluation and treatment of hand problems, prepared by the American Society for Surgery of the Hand. This convenient, portable manual provides all the essential information that surgeons and physicians need, including details on hand anatomy, thorough instructions for physical examination of the hand, and step-by-step guidelines for the diagnosis and treatment of all disorders and injuries. Also included are chapters on emergency room assessment, operating room setup, and postoperative care. The text is written in an easy-to-follow style and illustrated with 172 drawings, photographs, and radiographs. A Brandon-Hill recommended title.

Musculoskeletal Sports and Spine Disorders

A Comprehensive Guide

Author: Stuart B. Kahn,Rachel Yinfei Xu

Publisher: Springer

ISBN: 3319505122

Category: Medical

Page: 477

View: 1084

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Fulfilling the need for an easy-to-use resource on managing musculoskeletal disorders and sports injuries, this book provides differential diagnostic workups with recommended gold standard evaluations that lead to a simple and accurate diagnosis, followed by first-line treatment options. Organized by five sections - head and neck, upper extremity, lower extremity, abdomen/pelvis with trunk and chest, and cervical, thoracic and lumbosacral spine - chapters present a concise summary and move on to a description of the most common symptoms, etiology, epidemiology and/or common causes if traumatic in nature. The best and most accepted diagnostic tests are illustrated, along with recommended evidence-based medicine and what may be done based on community standards of care. Treatment options will be listed in order of the most conservative to the most aggressive. This complete reference will provide primary care, physiatry, and ER physicians, residents, PA’s and students a simple and practical approach for clinical and academic use.

Postgraduate Orthopaedics

The Candidate's Guide to the FRCS (Tr & Orth) Examination

Author: Paul A. Banaszkiewicz,Deiary F. Kader

Publisher: Cambridge University Press

ISBN: 1316586405

Category: Medical

Page: N.A

View: 5768

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The third edition of Postgraduate Orthopaedics has been fully updated, revised and expanded to meet the challenges of a continually changing exam format, providing detailed core orthopaedic knowledge and insight into tactics and pre-exam planning to increase a candidate's chance of success. Written by a core of authors chosen specifically for their knowledge of the key factors for exam success, this edition includes more illustrations and diagrams and additional exam-focused material for the trickier areas of the syllabus. The trauma chapter has been separated into four distinct sections to improve the overall trauma content. The book also includes a dedicated chapter on what books to read, reflecting the fact that this area has become more complicated in recent years, and an applied basic science chapter, which focuses on basic science viva questions in detail. This guide continues to evolve and has established itself as the definitive text for the FRCS (Tr & Orth) exam.


Treatment of Chronic Pain by Interventional Approaches

the AMERICAN ACADEMY of PAIN MEDICINE Textbook on Patient Management

Author: Timothy R. Deer,Michael S. Leong,Asokumar Buvanendran,Philip S. Kim,Sunil J. Panchal

Publisher: Springer

ISBN: 1493918249

Category: Medical

Page: 562

View: 2650

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From reviews of Deer, eds., Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches: "Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches is a major textbook... [I]t should be a part of all departmental libraries and in the reference collection of pain fellows and pain practitioners. In fact, this text could be to pain as Miller is to general anesthesia." Journal of Neurosurgical Anesthesiology Edited by master clinician-experts appointed by the American Academy of Pain Medicine, this is a soft cover version of the Interventional sections of the acclaimed Deer, eds., Comprehensive Treatment of Chronic Pain by Medical, Interventional, and Integrative Approaches. It is intended as a primary reference for busy clinicians who seek up-to-date and authoritative information about interventional approaches to treating chronic pain. State-of-the-art coverage of full range of techniques: neural blockades, neurolysis blocks, and neurostimulation Review of clinically relevant anatomy and physiology "Key Points" preview contents of each chapter

Essential Surgery E-Book

Problems, Diagnosis and Management: With STUDENT CONSULT Online Access

Author: Clive R. G. Quick,Joanna B Reed,Simon J.F. Harper,Kourosh Saeb-Parsy,Philip J. Deakin

Publisher: Elsevier Health Sciences

ISBN: 0702054836

Category: Medical

Page: 720

View: 6904

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Essential Surgery is a comprehensive and highly illustrated textbook suitable for both clinical medical students as well junior surgical trainees, preparing for postgraduate qualifications in surgery such as the MRCS. Covering general surgery, trauma, orthopaedics, vascular surgery, paediatric surgery, cardiothoracic surgery and urology, it incorporates appropriate levels of basic science throughout. The book is ideal for modern clinical courses as well as being a practical manual for readers at more advanced levels. Its main aim is to stimulate the reader to a greater enjoyment and understanding of the practice of surgery. Essential Surgery incorporates a problem-solving approach wherever possible, emphasising how diagnoses are made and why particular treatments are used. The pathophysiological basis of surgical diseases is discussed in relation to their management, acting as a bridge between basic medical sciences and clinical problems. The uniformity of the writing style and the clarity of elucidation will encourage continued reading, while the emphasis on the principles of surgery will enable a real understanding of the subject matter. The book’s extensive use of original illustrations, boxes and tables emphasises important concepts and will aid revision. The principles of operative surgery and perioperative care are explained together with outlines of common operations, enabling students and trainee surgeons to properly understand procedures and to participate intelligently in the operating department. A major revision of the text has taken full account of the progressive evolution of surgery and includes new concepts that have advanced medical understanding. New topics have been added to ensure the book’s contents match the curriculum of the UK Intercollegiate MRCS examination, including patient safety, surgical ethics, communication, consent, clinical audit and principles of research. The broad experience of surgical teaching and training of two new authors has brought a fresh perspective on the book’s contents and its presentation. New consensus guidelines for managing common disorders have been incorporated where appropriate.

The Biceps and Superior Labrum Complex

A Clinical Casebook

Author: Nikhil N. Verma,Eric J. Strauss

Publisher: Springer

ISBN: 3319549340

Category: Medical

Page: 229

View: 2408

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Comprised exclusively of clinical cases covering the management of injuries to the biceps tendon and superior labrum, this concise, practical casebook will provide clinicians in orthopedics and sports medicine with the best real-world strategies to properly diagnose and treat the various types of injuries they may encounter. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome and clinical pearls and pitfalls. Cases included illustrate different surgical management strategies for acute and chronic biceps tendon ruptures, anterior shoulder pain, subscapularis tears, proximal tenodesis, synovial chondromatosis and SLAP lesions type 1 through 4. Pragmatic and reader-friendly, The Biceps and Superior Labrum Complex: A Clinical Casebook will be an excellent resource for orthopedic surgeons, sports medicine practitioners and physical therapists alike.

Dupuytren’s Contracture

A Clinical Casebook

Author: Marco Rizzo

Publisher: Springer

ISBN: 3319238418

Category: Medical

Page: 273

View: 494

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Comprised exclusively of clinical cases involving Dupuytren’s contracture, this concise, practical casebook will provide clinicians in orthopedics and hand surgery with the best real-world strategies to properly diagnose and treat this recurrent disease of the fascia. Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome and clinical pearls and pitfalls. Initial chapters discuss non-operative treatments ranging from orthosis/tissue mobilization, corticosteroid injections, needle aponeurotomy and collagenase injections. Various surgical interventions follow, including fasciotomy, fasciectomy, open palm, and dermatofasciectomy. Chapters discussing the use of skin grafting, illustrating the special challenges associated with revision surgery, and “end of the line” interventions such as arthrodesis and amputation are also included. Less common aspects of Dupuytren’s are reviewed as well, as are cases that address treatment and special consideration in younger patients, the role/use of dynamic external fixators in Dupuytren’s care, correction of distal interphalangeal (DIP) joint contractures and treatment of dorsal finger (Garrod’s) nodes. Pragmatic and reader-friendly, Dupuytren’s Contracture: A Clinical Casebook will be an excellent resource for orthopedic and hand surgeons alike.

Dupuytren’s Disease

Pathobiochemistry and Clinical Management

Author: Alfred Berger,Axel Delbrück,Peter Brenner,Rolf Hinzmann

Publisher: Springer Science & Business Media

ISBN: 3642785174

Category: Medical

Page: 301

View: 3683

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In this volume a distinguished group of internationally renowned clinicians and basic researchers discuss the present state of knowledge of the etiologyand pathogenesis of Dupuytren's contracture, a disease responsible for a considerable portion of disabilities within the working population allover the world. Although the riddle of how the contracture of the palmar fascia develops is still unsolved, the data on the pathobiochemistry and clinic of Dupuytren's Disease achieved in recent years has led to a better understanding of the biochemical and morphological processes underlying the deformation and malfunction of the afflicted tissues. Research in Dupuytren's Disease now enters the era of molecular medicine, which opens up new experimental means of studying the pathological changes which occur during the formation of the contracture on a molecular level. In particular, data are presented as to the role of specific biological macromolecules influencing the phenotype expression of the palmar fascia cells which are involved in autoimmune reactions and present both at the cell surface as well as in the extracellular matrix to regulate cell-to-cell and cell-to-matrix interactions. In vitro cell culture models to investigate fibro-cytic modulations are available and havebeen applied to study the effects of specific biological molecules on isolated cells from healthy palmar fascia and Dupuytren's contracture. Complementary evaluations of morphological, epidemiological, and clinical data contribute essentially to the present understanding of the etiology and pathogenesis of Dupuytren's Disease. This comprehensive and informative summary of the state of the art is completed by numerous references affixed to the individual contributions.