Handbook of Research on Critical Examinations of Neurodegenerative Disorders

Author: Uddin, Md. Sahab,Amran, Md. Shah

Publisher: IGI Global

ISBN: 1522552839

Category: Medical

Page: 597

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Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and future opportunities and challenges in this growing field. The Handbook of Research on Critical Examinations of Neurodegenerative Disorders is a critical scholarly resource that provides an extensive explanation of various neurodegenerative disorders based on existing studies to clarify etiology, pathological mechanisms, diagnosis, therapeutic interventions, as well as current status and future opportunities and challenges. Featuring coverage on a broad range of topics such as dementia, mitochondrial dysfunction, and risk factors, this book is geared towards neurobiologists, neuropsychologists, neurophysiologists, neuropathologists, medical professionals, academicians, and researchers seeking research on the complexity of neurodegenerative disorders.

Psychosocial Studies of the Individual's Changing Perspectives in Alzheimer's Disease

Author: Dick-Muehlke, Cordula

Publisher: IGI Global

ISBN: 1466684798

Category: Health & Fitness

Page: 435

View: 3142

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Cognitive impairment, through Alzheimer’s disease or other related forms of dementia, is a serious concern for afflicted individuals and their caregivers. Understanding patients’ mental state and combatting social stigmas are important considerations in caring for cognitively impaired individuals. Psychosocial Studies of the Individual's Changing Perspectives in Alzheimer's Disease describes programs and strategies that professional and family caregivers can implement to engage and improve the quality of life of persons suffering from cognitive impairment. Including real-world cases by international experts and a personal approach to the subject, this book is an important resource for caregivers, researchers, and families living with dementia.

Animal Models for the Study of Human Disease

Author: P. Michael Conn

Publisher: Academic Press

ISBN: 0128096993

Category: Medical

Page: 1198

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Animal Models for the Study of Human Disease, Second Edition, provides needed information on model sharing, animal alternatives, animal ethics and access to databanks of models, bringing together common descriptions of models for busy researchers across biomedical and biological sciences. Offering easily searchable advantages and disadvantages for each animal model and organized by disease topics, this resource aids researchers in finding the best animal model for research in human disease. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives, and animal ethics Covers a broad range of animal models used in research for human disease Contributed by leading experts across the globe Expanded coverage of diabetes and neurological diseases

Central Nervous System Diseases

Innovative Animal Models from Lab to Clinic

Author: Dwaine F. Emerich,Reginald L. Dean III,Paul R. Sanberg

Publisher: Springer Science & Business Media

ISBN: 1592596916

Category: Medical

Page: 512

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Prominent experimentalists critically review the animal models widely used in developing powerful new therapies for central nervous system diseases. Coverage includes novel uses of animal models of Alzheimer's, Parkinson's, and Huntington's diseases, and studies of aging. Techniques that rely heavily on behavioral analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology, are thoroughly explicated, as are models developed for more acute neurological conditions, including traumatic brain injury and stroke. Comprehensive and authoritative, Central Nervous System Diseases: Innovative Animal Models from Lab to Clinic offers neuroscientists, pharmacologists, and interested clinicians a unique survey of the most productive animal models of the leading neurological diseases currently employed to develop today's innovative drug therapies.

Advanced Methodologies and Technologies in Medicine and Healthcare

Author: Khosrow-Pour, D.B.A., Mehdi

Publisher: IGI Global

ISBN: 1522574905

Category: Medical

Page: 591

View: 9414

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Advancements in medical and healthcare technologies pave the way to improving treatments and diagnoses while also streamlining processes to ensure the highest quality care is given to patients. In the last few decades, revolutionary technology has radically progressed the healthcare industry by increasing life expectancy and reducing human error. Advanced Methodologies and Technologies in Medicine and Healthcare provides emerging research on bioinformatics, medical ethics, and clinical science in modern applications and settings. While highlighting the challenges medical practitioners and healthcare professionals face when treating patients and striving to optimize their processes, the book shows how revolutionary technologies and methods are vastly improving how healthcare is implemented globally. This book is an important resource for medical researchers, healthcare administrators, doctors, nurses, biomedical engineers, and students looking for comprehensive research on the advancements in healthcare technologies.

Guide to the Primary Care of Neurological Disorders

Author: A. John Popp

Publisher: Thieme

ISBN: 1604063297

Category: Medical

Page: 456

View: 4136

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Synthesizing the expert clinical advice of specialists who treat disorders of the nervous system, this book is an accessible, single-volume resource for primary care physicians requiring practical information on a range of neurological disorders. A Guide to the Primary Care of Neurological Disorders provides readers with a firm foundation in neuroscience concepts that will enable them to make timely diagnostic, treatment, and referral decisions about common symptoms, including chronic pain, headache, seizures, numbness, and dizziness. Additional chapters cover specific categories of neurological disease, providing the reader with concise descriptions of the clinical manifestations, examination techniques, and treatment options for each. Features: An outline at the start of each chapter aids rapid location of topics of interest Thorough coverage of history-taking and the physical examination Pearls and Pitfalls at the end of each chapter review fundamental concepts and provide helpful guideposts for managing each clinical situation Packed with essential information on clinical neurosciences, this comprehensive book is ideal for primary care physicians, nurse practitioners, physicians' assistants, residents in primary care specialties, and medical students.A co-publication of Thieme and the American Association of Neurological Surgeons)

The Neurologic Examination

Scientific Basis for Clinical Diagnosis

Author: Hiroshi Shibasaki MD, PhD,Mark Hallett MD

Publisher: Oxford University Press

ISBN: 0190240989

Category: Medical

Page: 352

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Whereas most book about the neurologic examination are disease and anatomy oriented, The Neurologic Examination: Scientific Basis for Clinical Diagnosis focuses on a pathophysiological approach to the nervous system. The authors emphasize that the scientific interpretation of symptoms obtained from carefully taking the patient's history and noting signs found during physical examination are essential in the diagnosis of neurologic diseases, even if laboratory testing, such as electrophysiology and neuroimaging, are more widely used. This book aims to provide a bridge from the basic sciences such as anatomy, physiology, pharmacology, and molecular biology to the neurologic symptoms. Neurologic examinations provide the foundation for diagnosis, and only after a thorough and expertly executed examination can one begin to incorporate laboratory testing and treatment. The Neurologic Examination: Scientific Basis for Clinical Diagnosis, based on the widely successful Japanese book Diagnosis of Neurological Diseases (Igakushoin, Japan, second edition 2013) by Dr. Shibasaki, hopes to revitalize the use of neurologic examinations before jumping into laboratory testing. Doing so can help cut down on time, patient and physician anxiety, and unnecessary testing expenses. This book is a must-read for all practicing neurologists, residents, and medical students. Key Features Include · The chapters are arranged in order of the actual steps in a neurologic examination; · Highly illustrated with figures and tables indicative of the neurologic signs and symptoms that may appear during the given step; and · 99 discussion boxes are inserted throughout to provide a more in-depth look at particular topics without interrupting the reading flow of the text.

Neurological Disorders

Course and Treatment

Author: Thomas Brandt

Publisher: Gulf Professional Publishing

ISBN: 9780121258313

Category: Medical

Page: 1574

View: 5492

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This single-volume reference covers the natural course, treatment, and management of all neurological diseases affecting the brain, spinal cord nerves and muscles. This comprehensive text reference seeks to assist physicians with treatment by providing an easy-to-use compendium covering the treatment and management of all neurological diseases along with details on the natural course of these diseases. Organized for ease of use and quick reference, each chapter presents a neurological disorder or key symptoms and systematically discusses the clinical syndrome and differential diagnosis, natural course, principles of therapy, and practical management of each. Key Features * Covers wide range of neurological conditions and potential treatments, including the evidence for and against each treatment * Describes the spontaneous course of neurological diseases along with discussion of the management of different stages and variants of a disorder * Presents special situations and exceptional cases in which alternative therapies should be considered

Neurodegenerative Diseases

Unifying Principles

Author: Jagan A. Pillai

Publisher: Oxford University Press

ISBN: 0190233567

Category:

Page: 360

View: 6901

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As the global population ages the impact of neurodegenerative diseases like Alzheimer's disease and Parkinson's disease are significant forces in shaping human health and quality of life in the 21st century. Insights into understanding these diseases, and knowing how to treat them are major frontiers of scientific research. Neurodegenerative Diseases: Unifying Principles is the result of a conceptual revolution over the last decade in our understanding of neurodegenerative diseases as sharing unifying features. There is an increasing appreciation of the common biological and pathological features across seemingly varied neurodegenerative diseases that entail protein misfolding dysfunction and its consequences over time. Providing an overview of this conceptual change is the main theme for the book. Conventional approach emphasize the differences among neurodegenerative disorders, here Drs. Cummings and Pillai compile the increasingly compelling evidence that these disorders share many features and that insights in one may be rapidly translated into advances in another. The goal is to accelerate understanding by showing linkages among biological, pathological, can clinical aspects of this class of diseases. This collection of 19, inter-related chapters, articulates and broadens our view of the unifying features that initiate and drive disease progression across a variety of neurodegenerative diseases over time. This book will serve as an outstanding sourcebook of insights from experts that have played key roles in this story.

Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease

Author: Roger N. Rosenberg,Juan M. Pascual

Publisher: Elsevier

ISBN: 0124105491

Category: Medical

Page: 1464

View: 303

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Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

Primer on Cerebrovascular Diseases

Author: Louis R. Caplan,José Biller,Megan C. Leary,Eng H. Lo,Ajith J Thomas,Midori Yenari,John H. Zhang

Publisher: Academic Press

ISBN: 0128030593

Category: Science

Page: 968

View: 2174

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Primer on Cerebrovascular Diseases, Second Edition, is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, presenting the information in a comprehensive and easily accessible manner. Numerous changes have occurred in the field since the publication of the first edition in 1997, particularly our understanding of the genetic aspects of cerebrovascular disease. This updated edition reflects the advances made over the last two decades, not only demonstrating the promise for therapy, but also for a molecular understanding of cerebrovascular diseases. The new edition includes new and expanded topics, including carotid stenting, Iatrogenic causes of stroke, axonal transport and injury, RNAIs, proteomics, and more. Provides concise chapters on topics in cerebral blood flow and metabolism, pathogenesis of cerebrovascular disorders, diagnostic testing, and management in a comprehensive and accessible format Written by international leading authorities on cerebral vasculature Provides up-to-date information on practical applications of basic research and the main clinical issues facing the community, such as axonal transport and proteomics

Functional Neurobiology of Aging

Author: Patrick R. Hof,Charles V. Mobbs

Publisher: Academic Press

ISBN: 9780080525587

Category: Science

Page: 960

View: 8880

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Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments. Organized by function, making it easy to find and understand the material Addresses impairments both associated with diseases and not associated with diseases Written by leading researchers in the field Most comprehensive source of information on the neurobiology of aging

Neurobehavioral Disorders of Childhood

An Evolutionary Perspective

Author: Robert Melillo,Gerry Leisman

Publisher: Springer Science & Business Media

ISBN: 1441912312

Category: Medical

Page: 447

View: 7378

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Attention deficit disorder, attention deficit hyperactive disorder, pervasive developmental disorder, obsessive-compulsive disorder, asperger's syndrome, and autism, to name but a few, may be viewed as points on a spectrum of developmental disabilities in which those points share features in common and possibly etiology as well, varying only in severity and in the primary anatomical region of dysfunctional activity. This text focuses on alterations of the normal development of the child. A working theory is presented based on what we know of the neurological and cognitive development in the context of evolution of the human species and its brain. In outlining our theory of developmental disabilities in evolutionary terms, the authors offer evidence to support the following notions: Bipedalism was the major reason for human neocortical evolution; Cognition evolved secondary and parallel to evolution of motricity; There exists an overlap of cognitive and motor symptoms; Lack of thalamo-cortical stimulation, not overstimulation, is a fundamental problem of developmental disabilities; A primary problem is dysfunctions of hemisphericity; Most conditions in this spectrum of disorders are the result of a right hemisphericity; Environment is a fundamental problem; All of these conditions are variations of the same problem; These problems are correctable; Hemisphere specific treatment is the key to success.

Fundamental Neuroscience

Author: Larry R. Squire

Publisher: Academic Press

ISBN: 0123858704

Category: Medical

Page: 1127

View: 9532

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Fundamental Neuroscience, 3rd Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts. A companion web site contains test questions, and an imagebank of the figures for ready use in presentations, slides, and handouts. Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! New to this edition: * 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness * Companion website with figures, web links to additional material, and test questions * Additional text boxes describing key experiments, disorders, methods, and concepts * Multiple model system coverage beyond rats, mice, and monkeys * Extensively expanded index for easier referencing

Neuroscience and Critique

Exploring the Limits of the Neurological Turn

Author: Jan De Vos,Ed Pluth

Publisher: Routledge

ISBN: 1317500237

Category: Psychology

Page: 244

View: 432

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Recent years have seen a rapid growth in neuroscientific research, and an expansion beyond basic research to incorporate elements of the arts, humanities and social sciences. It has been suggested that the neurosciences will bring about major transformations in the understanding of ourselves, our culture and our society. In academia one finds debates within psychology, philosophy and literature about the implications of developments within the neurosciences, and the emerging fields of educational neuroscience, neuro-economics, and neuro-aesthetics also bear witness to a ‘neurological turn’ which is currently taking place. Neuroscience and Critique is a ground-breaking edited collection which reflects on the impact of neuroscience in contemporary social science and the humanities. It is the first book to consider possibilities for a critique of the theories, practices, and implications of contemporary neuroscience. Bringing together leading scholars from several disciplines, the contributors draw upon a range of perspectives, including cognitive neuroscience, critical philosophy, psychoanalysis, and feminism, and also critically examine several key ideas in contemporary neuroscience, including: The idea of "neural personhood" Theories of emotion in affective neuroscience Empathy, intersubjectivity and the notion of "embodied simulation" The concept of an "emo-rational" actor within neuro-economics. The volume will stimulate further debate in the emerging field of interdisciplinary studies in neuroscience, and will appeal to researchers and advanced students in a range of disciplines including critical psychology, philosophy, and critical studies.

Small Animal Neurological Emergencies

Author: Simon Platt,Laurent Garosi

Publisher: CRC Press

ISBN: 184076614X

Category: Medical

Page: 672

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This new book deals systematically with the assessment and treatment of small animal neurological patients in light of latest research findings and greatly improved imaging techniques. The authors first discuss step-wise neurological and systemic approaches to common emergency cases—examination, critical care and rapid assessment—based on presenting signs. They then deal in depth with the pathophysiology, treatment options and likely prognoses of each of the more common types of neurological emergency, be it vascular accident, infection, trauma, seizure, acute disease or neoplasia. Detailed support techniques and therapies are provided on emergency anaesthesia, pain management, fluid therapy, post-operative care and physical rehabilitation. The book will appeal to small animal practitioners, specialists, residents, course directors and students interested in neurology, emergency medicine and critical care, internal medicine, imaging and pathology.

Neurological Disorders

Public Health Challenges

Author: World Health Organization

Publisher: World Health Organization

ISBN: 9241563362

Category: Medical

Page: 218

View: 7056

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Although there are several gaps in understanding the many issues related to neurological disorders, we know enough to be able to shape effective policy responses to some of the most common. This book describes and discusses the increasing public health impact of common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, neuroinfections, neurological disorders associated with malnutrition, pain associated with neurological disorders, Parkinson's disease, stroke and traumatic brain injuries. It provides information and advice on public health interventions that may reduce their occurrence and consequences, and offers health professionals and planners the opportunity to assess the burden caused by these disorders. The clear message that emerges is that unless immediate action is taken globally, the neurological burden is likely to become an increasingly serious and unmanageable.


Gut

The Inside Story of Our Body's Most Underrated Organ (Revised Edition)

Author: Giulia Enders

Publisher: Greystone Books Ltd

ISBN: 1771643781

Category: Health & Fitness

Page: 304

View: 2362

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In this updated edition of a worldwide bestseller, Giulia Enders reveals the secrets and science of the digestive system—including new research on the connection between the gut and the brain. For too long, the gut has been the body’s most ignored and least appreciated organ. But it does more than just dirty work; our gut is at the core of who we are. With quirky charm, science star and medical doctor Giulia Enders explains the gut’s magic, answering questions like: Why does acid reflux happen? What’s really up with gluten and lactose intolerance? How does the gut affect obesity and mood? A new section on the brain-gut axis dives into groundbreaking discoveries of psychobiotics – microbes with psychological effects that can influence conditions like depression and even stress. Aided with cheerful illustrations by Enders’s sister Jill, this beguiling manifesto will make you finally listen to those butterflies in your stomach: they’re trying to tell you something important.

Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders

Author: Gupta, Sanjeev Kumar,Venkatesan, Srinivasan,Goswami, S.P.,Kumar, Rajeev

Publisher: IGI Global

ISBN: 1522570055

Category: Medical

Page: 394

View: 4520

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Neurodevelopmental disorders encompass a group of conditions that can typically manifest during early childhood. These include intellectual disabilities, communication disorders, autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), specific learning disorder (SLD), and motor disorders. Early identification and assessment can be a valuable tool in determining diagnosis, prognosis, functional abilities, and formulating clinical intervention for both children and adults with neurodevelopmental disorders. Emerging Trends in the Diagnosis and Intervention of Neurodevelopmental Disorders is an essential reference source that discusses and disseminates contributions covering recent trends in diagnosis, assessment, and intervention techniques. Featuring research on topics such as clinical linguistics, neural connectivity, and animal-assisted therapy, this book is ideally designed for speech pathologists, social workers, occupational therapists, psychologists, psychiatrists, neurologists, pediatricians, researchers, clinicians, and academicians seeking coverage on neural and developmental disorder identification and strategies for clinician support and therapies.