Ophthalmic Drugs

Diagnostic and Therapeutic Uses

Author: Graham Hopkins,Richard M. Pearson

Publisher: Elsevier Health Sciences

ISBN: 0750688645

Category: Medical

Page: 331

View: 9270

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Providing information on ocular therapeutics, this edition offers a basic grounding in pharmacological principles and drug types. It then moves on to common ocular conditions, showing how they can be diagnosed and treated using ocular therapeutics. It also contains many clinical notes and ready-reference tables.

The Actions and Uses of Ophthalmic Drugs

A Textbook for Students and Practitioners

Author: P. H. O'Connor Davies

Publisher: Elsevier

ISBN: 1483192202

Category: Medical

Page: 398

View: 9670

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The Actions and Uses of Ophthalmic Drugs: A Textbook for Students and Practitioners, Second Edition provides pertinent information in relation to concepts in pharmacology, the formulation and application of ophthalmic drugs, and adverse ocular effects of systemic medication. This book discusses the preparations used in contact lens practice. Organized into 17 chapters, this edition begins with an overview of the primary systems of drug classification according to their actions or effects, or on the basis of their chemistry. This text then presents a detailed discussion on the actions and uses of ophthalmic autonomic drugs. Other chapters consider the structure and function of the involuntary nervous system in the orbital region. This book discusses as well the two main classifications of ophthalmic drugs, namely, therapeutic and diagnostic. The final chapter deals with the clinical significance of medication-induced ocular adverse effects. This book is a valuable resource for ophthalmologists, students, and practitioners.

Ophthalmic Drug Delivery Systems, Second Edition

Author: Ashim K. Mitra

Publisher: Informa Health Care

ISBN: 0824741242

Category: Medical

Page: 847

View: 4971

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The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.

Clinical Ocular Pharmacology

Author: Jimmy D. Bartlett

Publisher: Elsevier

ISBN: 1483193918

Category: Medical

Page: 944

View: 3477

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Clinical Ocular Pharmacology, Second Edition covers the diagnostic and therapeutic clinical procedures in the administration of drugs to the eye. This book is organized into five parts encompassing 35 chapters that evaluate the basic pharmacologic principles that govern the different types of ophthalmic drugs. It addresses the pharmacologic agents useful in the diagnosis and treatment of ocular diseases. Some of the topics covered in the book are the basic science of ocular pharmacology; clinical administration of ocular drugs; drugs affecting the autonomic nervous system; types of local anesthetics; review of anti-inflammatory drugs; and examination of inhibitors of aqueous formation. Other parts deal with the development of contact lens solution in clinical practice and the pharmacologic management of strabismus. These topics are followed by discussions of the legal basis of using drugs in optometry and the systemic effects of ocular drugs. The concluding part is devoted to the diseases of the optic nerve. The book can provide useful information to doctors, optometrists, pediatricians, students, and researchers.

Drugs in Ophthalmology

Author: Donald S. Fong,Simon K Law,Ursula M. Schmidt-Erfurth

Publisher: Springer Science & Business Media

ISBN: 3540300473

Category: Medical

Page: 233

View: 9304

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Written by the world’s leading experts in the field Concise, easy to use handbook for quick reference in the prescription process Well-structured with separate sections on antibiotics, antivirals, antifungals, anesthetics and immunosuppressants Lists medication, dosage, side-effects and contraindications Separate chapter for pregnant women, since different rules apply Appeals to a large target group, including residents and experts in Ophthalmology, Optometry, Internal Medicine and Pharmacology International approach – the countries of use are specified for each drug

Ocular Drugs Handbook

An Easy Reference Guide to Eye Medications

Author: Kofi Oteng Gyang

Publisher: N.A

ISBN: 9781434345332

Category: Health & Fitness

Page: 189

View: 608

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author: Kofi Oteng Gyang The Ocular Drug handbook provides a quick, concise and easy reference guide to ophthalmic drugs used in the world of today. This book classifies all ophthamic drugs into their different categories of usage: anti-allergic, anti-bacterials, anti-inflammatory, anti-inflammatory cum anti-bacterials, anti-viral, anti-glaucoma, anti-fungals and dry eye therapy agents. It then presents concise information about their modes of action, commercial availability, dosage and contra-indications. Topical ocular drugs used in pediatrics are also presented. This is a precious handbook for all health care professionals, particularly eye doctors, ophthalmic nurses, ophthalmology and optometric students as well as residents. It is equally a valuable tool for anyone interested in ocular health, ocular pathology and ocular disease treatment. It will help many of our professional colleagues in different countries solve many of the intractable problems that they encounter daily in their practices

Ocular Therapeutics

Eye on New Discoveries

Author: Thomas Yorio,Abbott Clark,Martin B Wax

Publisher: Academic Press

ISBN: 9780080556772

Category: Science

Page: 536

View: 4638

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Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future. * Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. * Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases. * Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway. * New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States

Ocular Transporters and Receptors

Their Role in Drug Delivery

Author: Ashim K Mitra

Publisher: Elsevier

ISBN: 190881831X

Category: Science

Page: 276

View: 7686

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Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this book the cutting edge research being carried out in this field is compiled and summarized. The book focuses on key areas, including the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye. Highly focused on ocular transporters Most up-to-date research compilation Detailed description of role of transporters and receptors in ocular drug discovery and delivery

Ophthalmic Drug Facts 2002

Author: Jimmy D. Bartlett,Richard G. Fiscella,Edward Bennett,Siet Jaanus,J. James Rowsey

Publisher: Lippincott Williams & Wilkins

ISBN: 9781574391138

Category: Medical

Page: 427

View: 1758

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This definitive source of current, objective drug information for eye care is organized by therapeutic categories detailing the practical material needed by eye-care practitioners, including actions, interactions, adverse reactions, contraindications, dosages, off-label usage, and patient information.

Ophthalmic Medications and Pharmacology

Author: Brian Duvall,Robert M. Kershner

Publisher: SLACK Incorporated

ISBN: 9781556427503

Category: Medical

Page: 130

View: 1906

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For those who are new to the subject, ocular pharmacology can be a difficult and sometimes overwhelming topic.nbsp; Ophthalmic Medications and Pharmacology, Second Edition is a reader-friendly guide that provides a quick review and basic clinical reference of ocular pharmacology. nbsp; In this updated and revised second edition, Drs. Duvall and Kershner present an overview to the medication and drugs found most commonly in ophthalmic practice without overwhelming those professionals new to the subject.nbsp; nbsp; Ophthalmic Medications and Pharmacology concisely reviews commonly used and prescribed medications, how they work, dosage, therapeutic use, and potential side effects.nbsp; This new edition also highlights key information for patients about the medications they encounter and are prescribed in the clinic. nbsp; Ophthalmic staff, students, and research professionals looking for an introduction and basic go-to guide will welcome having a copy of Ophthalmic Medications and Pharmacology by their side. New to this edition: ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; An appendix focused on the drug approval process. ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; A chapter on retinal therapies. ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; Study icons to assist in the learning process. ·nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; New coverage of vasoconstrictors. nbsp; nbsp;

Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology

Author: Frederick T. Fraunfelder,Frederick W. Fraunfelder Jr.,Wiley A. Chambers

Publisher: Elsevier Health Sciences

ISBN: 0323319858

Category: Medical

Page: 424

View: 5713

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Ideal for ophthalmologists, optometrists and busy clinicians, Drug-Induced Ocular Side Effects provides the clinically relevant information you need to diagnose and manage chemical and drug-related ocular problems. An easily accessible format, meticulous revisions and comprehensive coverage of all drugs’ generic and trade names, primary uses, ocular and systemic side effects, and clinical significance make this best-selling resource the ideal reference for quick, on-the-spot consultation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Manage any challenge in ocular toxicology with extensive coverage of principles of therapy; ocular drug delivery; methods to evaluate drug-induced visual side effects; and the role of electrophysiology and psychophysics. Benefit from the masterful guidance and global perspective of world authorities in the field who provide need-to-know information on all aspects of ocular toxicology—all in one concise reference. Confer with the WHO classification system to determine whether a particular side effect is certain, probable, or likely to occur. Zero in on the key information you need to know with highly templated, concise chapters. Apply the latest knowledge and treatments for newly recognized Adverse Drug Reactions (ADR). Identify which ADR’s are clinically relevant and what to do about them. Experience clinical scenarios with vivid clarity through a wealth of new and updated clinical photographs that provide unmatched, visual diagnostic guidance. Recognize and avoid drug-induced ocular side effects with data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden). Stay up to date and provide state-of-the-art care with the latest information on approved medications.

Ophthalmic Disease Mechanisms and Drug Discovery

Author: Kang Zhang

Publisher: World Scientific

ISBN: 9814663085

Category:

Page: 232

View: 7939

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This invaluable book presents a concise discussion on the most important topics of ophthalmology ? mechanism of ophthalmic diseases, imaging techniques used for diagnosis, novel therapies and drug delivery systems. It also covers current knowledge about anti-VEGF therapies that revolutionized neovascular AMD treatment, anti-inflammatory and dry eye treatment, as well as nanoparticles use of drug delivery. Written by experts in ophthalmology, this unique volume provides a comprehensive overview of the latest research in the field. This is an essential reading that will provide up-to-date reference to practicing physicians and current knowledge to residents and students. Contents: Introduction (Kang Zhang)Pathology and Mechanism of Eye Diseases (Katherine J Wert, Heike Kroeger, Frances Wu, Stephen H Tsang and Jonathan H Lin)Ophthalmic Imaging (Colin S Tan and SriniVas R Sadda)Pharmacogenomics of Response to Anti-VEGF Therapy in Exudative Age-Related Macular Degeneration (Seanna Grob, Kang Zhang and Sophie J Bakri)Dry Eye Therapy (Seanna Grob, Igor Kozak and Kang Zhang)Ocular Inflammation Therapy (Seanna Grob, Igor Kozak and Kang Zhang)Nanoparticles for Ocular Drug Delivery (Qiangzhe Zhang, Jieming Li, Weiwei Gao and Liangfang Zhang) Readership: Undergraduate students interested in ophthalmology, medical students, PhD students, practicing physicians, doctors and residents (in the field of ophthamology, or any other field, if they would like to contribute to their knowledge about ophthalmic diseases and treatments). Eye;Ocular Diseases;Dry Eye Disease;Adult Macular Degeneration (AMD);Glaucoma;Fluorescein Angiography;Indocyanine Green Angiography;Optical Coherence Tomography (OCT);Autofluorescence;Widefield Imaging;Anti-VEGF Therapy;Anti-inflammatory

Ocular Therapeutics

Author: Ashok Garg

Publisher: JP Medical Ltd

ISBN: 9350903202

Category: Medical

Page: 1094

View: 3656

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The third edition of Ocular Therapeutics brings practitioners up to date with the latest advances in ophthalmic drugs. Divided into three sections, the book begins with discussion on the physiology of the eye, drug administration and the fundamental role of ocular therapeutics. The second section examines the application of ocular therapeutics in ophthalmic surgery for many different disorders and the final section discusses recent advances and future developments. This new edition has been fully updated with the addition of new drugs and delivery systems, covering all groups of drugs used worldwide in different clinical conditions of the eye. Written by recognised international experts, many from the USA, the book is presented in an easy to read format and includes nearly 430 well-illustrated colour figures, tables, flow diagrams and chemical formulas. Key points New edition bringing ophthalmologists up to date with latest advances in ophthalmic drugs Includes new drugs and delivery systems for all groups of drugs used worldwide Written by recognised international experts Nearly 430 figures, tables, flow diagrams and chemical formulas Previous edition published in 2006

Pharmacology of Ocular Therapeutics

Author: Thirumurthy Velpandian

Publisher: Springer

ISBN: 3319254987

Category: Medical

Page: 535

View: 3090

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This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular drug therapy by compiling all key aspects of the pharmacology, toxicology, pharmaceutical science, ocular biochemistry and cell biology of these agents. Chapters detail drug transfer across barriers, systemic toxicity of topically applied drugs, autonomic drugs used for diagnostics, as well as anti-inflammatory, antiallergic, glaucoma and antimicrobial therapies, and avenues for the development of new ocular drugs. Applications of extemporaneously prepared formulations are described to inform day-to-day clinical practice. The use of mucoadhesive polymers in tear substitutes, ocular drug delivery systems, stem cell therapy, pharmacogenomics and antiangiogenic ocular chemotherapy are also explored. The book also provides insights from drugs of herbal origin, and a historical perspective on drugs for ocular use. Practicing and resident ophthalmologists, optometrists, pharmacists, nursing professionals, scholars in ocular drug research and students will equally benefit from this comprehensive guide.

Ophthalmic drug delivery systems

ä symposium

Author: Academy of Pharmaceutical Sciences. Industrial Pharmaceutical Technology Section

Publisher: N.A

ISBN: N.A

Category: Business & Economics

Page: 137

View: 2865

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Ophthalmic Drug Delivery

Biopharmaceutical, Technological and Clinical Aspects

Author: M.F. Saettone,M. Bucci,P. Speiser

Publisher: Springer Science & Business Media

ISBN: 1475741758

Category: Medical

Page: 197

View: 6253

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Ocular Transporters in Ophthalmic Diseases and Drug Delivery

Author: Joyce Tombran-Tink,Colin J. Barnstable

Publisher: Springer Science & Business Media

ISBN: 9781597453752

Category: Medical

Page: 467

View: 5574

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In this exceptionally important new work, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium and nutrients across the retinal pigment epithelium.


Drug Product Development for the Back of the Eye

Author: Uday B. Kompella,Henry F. Edelhauser

Publisher: Springer Science & Business Media

ISBN: 1441999205

Category: Medical

Page: 592

View: 7763

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This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage forms Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devices Intravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of delivery Physical methods including iontophoresis for drug delivery Rational selection of routes of administration and delivery systems Noninvasive and continuous drug monitoring Regulatory path to drug product development Clinical endpoints for drug product development Emerging and existing drugs and drug targets Drug Product Development for the Back of the Eye is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering.

Biopharmaceutics of Ocular Drug Delivery

Author: Peter Edman

Publisher: CRC Press

ISBN: 9780849372964

Category: Medical

Page: 224

View: 3487

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A significant new book on drug delivery to the eye Biopharmaceutics of Ocular Drug Delivery examines the current physiological, anatomical, pharmaceutical/technological, and biopharmaceutical knowledge on ocular drug delivery. Leading ophthalmic researchers cover topics such as the formulation and usage of ophthalmic solutions and suspensions, the influence of surfactants and preservatives on ocular drug absorption, and new techniques that include bioadhesion and the use of hyaluronic acid as an ophthalmic vehicle. Promising research on new delivery systems for improved drug therapy is highlighted, including new pharmaceutical vehicles, inserts, liposomes, nanoparticles, and prodrugs. Biopharmaceutics of Ocular Drug Delivery is one of the few books available on drug delivery to the eye and will be an important reference for ophthalmologists, pharmacologists, pharmaceutical researchers, and other scientists interested in the topic.