The Emergence of Life

From Chemical Origins to Synthetic Biology

Author: Pier Luigi Luisi

Publisher: Cambridge University Press

ISBN: 1139455648

Category: Science

Page: N.A

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The origin of life from inanimate matter has been the focus of much research for decades, both experimentally and philosophically. Luisi takes the reader through the consecutive stages from prebiotic chemistry to synthetic biology, uniquely combining both approaches. This book presents a systematic course discussing the successive stages of self-organisation, emergence, self-replication, autopoiesis, synthetic compartments and construction of cellular models, in order to demonstrate the spontaneous increase in complexity from inanimate matter to the first cellular life forms. A chapter is dedicated to each of these steps, using a number of synthetic and biological examples. With end-of-chapter review questions to aid reader comprehension, this book will appeal to graduate students and academics researching the origin of life and related areas such as evolutionary biology, biochemistry, molecular biology, biophysics and natural sciences.

The Emergence of Life

From Chemical Origins to Synthetic Biology

Author: Pier Luigi Luisi

Publisher: Cambridge University Press

ISBN: 1316571661

Category: Science

Page: N.A

View: 4932

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Addressing the emergence of life from a systems biology perspective, this new edition has undergone extensive revision, reflecting changes in scientific understanding and evolution of thought on the question 'what is life?'. With an emphasis on the philosophical aspects of science, including the epistemic features of modern synthetic biology, and also providing an updated view of the autopoiesis/cognition theory, the book gives an exhaustive treatment of the biophysical properties of vesicles, seen as the beginning of the 'road map' to the minimal cell - a road map which will develop into the question of whether and to what extent synthetic biology will be capable of making minimal life in the laboratory. Fully illustrated, accessibly written, directly challenging the reader with provocative questions, offering suggestions for research proposals, and including dialogues with contemporary authors such as Humberto Maturana, Albert Eschenmoser and Harold Morowitz, this is an ideal resource for researchers and students across fields including bioengineering, evolutionary biology, molecular biology, chemistry and chemical engineering.

Life's Origin

The Beginnings of Biological Evolution

Author: J. William Schopf

Publisher: Univ of California Press

ISBN: 9780520233904

Category: Science

Page: 208

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This volume explores the historical and current theories about the origin of life, addressing in particular the three key puzzles of how and when life began on Earth and in what form.

Chemical Synthetic Biology

Author: Pier Luigi Luisi,Cristiano Chiarabelli

Publisher: John Wiley & Sons

ISBN: 9781119990307

Category: Science

Page: 392

View: 1287

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Chemistry plays a very important role in the emerging field of synthetic biology. In particular, chemical synthetic biology is concerned with the synthesis of chemical structures, such as proteins, that do not exist in nature. With contributions from leading international experts, Chemical Synthetic Biology shows how chemistry underpins synthetic biology. The book is an essential guide to this fascinating new field, and will find a place on the bookshelves of researchers and students working in synthetic chemistry, synthetic and molecular biology, bioengineering, systems biology, computational genomics, and bioinformatics.

Charles Darwin

Die Entstehung der Arten

Author: Paul Wrede,Saskia Wrede

Publisher: John Wiley & Sons

ISBN: 352766873X

Category: Science

Page: 599

View: 859

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Das grundlegende Werk von Darwin On the Origin of Species liegt hier in der originalen Übersetzung durch Julius Victor Carus vor, erweitert durch zahlreiche Erläuterungen, aussagekräftige Abbildungen sowie wichtige historische Bezüge. Die Entstehung der Arten von Darwin ist für die heutige Leserschaft häufig schwierig zu verstehen. Eine hilfreiche Unterstützung erfolgt durch die farbliche Hervorhebung entscheidender Textstellen und viele fachliche Erklärungen. Darwins Analysen und Bewertungen aus den Gebieten der Botanik, Zoologie, Verhaltenslehre, Paläontologie und Entwicklungsbiologie werden in acht Beiträgen namhafter Fachwissenschaftler im Licht der gegenwärtigen Forschung beleuchtet und so wird erst die ungeheure Bedeutung und Weitsicht seines Werkes offensichtlich. Endlich liegen jetzt die Übersetzungen der beiden ebenso bahnbrechenden Aufsätze von Alfred Russel Wallace vor: der Sarawak- und Ternate-Essay. Wallace war neben Darwin der bedeutendste Evolutionsforscher seiner Zeit. Seine Arbeiten zur Evolutionsbiologie, die im Angelsächsischen hoch geschätzt sind, können als durchaus gleichrangig zu Darwins berühmtester Schrift angesehen werden. Ulrich Kutschera eröffnet das Buch mit einem Geleitwort und Reinhold Leinfelder schließt es mit einem Ausblick zur Bedeutung der Evolutionstheorie für die Zukunft des Menschen ab. Das Buch ist daher nicht nur eine unverzichtbare Lernhilfe für Schüler und Studenten, die sich mit der Evolutionsbiologie beschäftigen, sondern zusätzlich auch eine spannende weiterführende Lektüre für alle Leser mit Interesse an Wissenschaftsgeschichte.

Heterocycles in Life and Society

An Introduction to Heterocyclic Chemistry, Biochemistry and Applications

Author: Alexander F. Pozharskii,Anatoly T. Soldatenkov,Alan R. Katritzky

Publisher: John Wiley & Sons

ISBN: 111997013X

Category: Science

Page: 400

View: 7273

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Heterocycles in Life and Society is an introduction to the chemistry of heterocyclic compounds, focusing on their origin and occurrence in nature, biochemical significance and wide range of applications. Written in a readable and accessible style, the book takes a multidisciplinary approach to this extremely important area of organic chemistry. Topics covered include an introduction to the structure and properties of heterocycles; the key role of heterocycles in important life processes such as the transfer of hereditary information, how enzymes function, the storage and transport of bioenergy, and photosynthesis; applications of heterocycles in medicine, agriculture and industry; heterocycles in supramolecular chemistry; the origin of heterocycles on primordial Earth; and how heterocycles can help us solve 21st century challenges. For this second edition, Heterocycles in Life and Society has been completely revised and expanded, drawing on a decade of innovation in heterocyclic chemistry. The new edition includes discussions of the role of heterocycles in nanochemistry, green chemistry, combinatorial chemistry, molecular devices and sensors, and supramolecular chemistry. Impressive achievements include the creation of various molecular devices, the recording and storage of information, the preparation of new organic conductors, and new effective drugs and pesticides with heterocyclic structures. Much new light has been thrown on various life processes, while the chemistry of heterocycles has expanded to include new types of heterocyclic structures and reactions, and the use of heterocyclic molecules as ionic liquids and proton sponges. Heterocycles in Life and Society is an essential guide to this important field for students and researchers in chemistry, biochemistry, and drug discovery, and scientists at all levels wishing to expand their scientific horizon.

Between Necessity and Probability: Searching for the Definition and Origin of Life

Author: Radu Popa

Publisher: Springer Science & Business Media

ISBN: 9783540204909

Category: Science

Page: 252

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Systematically explores the early origins and basic definition of life. Investigates the major theories of the origins of life in light of modern research with the aim of distinguishing between the necessary and the optional and between deterministic and random influences in the emergence of what we call ‘life.’ Treats and views life as a cosmic phenomenon whose emergence and driving force should be viewed independently from its Earth-bound natural history. Synthesizes all the fundamental life-related developments in a comprehensive scenario, and makes the argument that understanding life in its broadest context requires a material-independent perspective that identifies its essential fingerprints

Mind and Life

Discussions with the Dalai Lama on the Nature of Reality

Author: Pier Luigi Luisi

Publisher: Columbia University Press

ISBN: 0231529708

Category: Religion

Page: 232

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For over a decade, a small group of scientists and philosophers members of the Mind and Life Institute have met regularly to explore the intersection between science and the spirit. At one of these meetings, the themes discussed were both fundamental and profound: can physics, chemistry, and biology explain the mystery of life? How do our philosophical assumptions influence science and the ethics we bring to biotechnology? And how does an ancient spiritual tradition throw new light on these questions? Pier Luigi Luisi not only reproduces this dramatic, cross-cultural dialogue, in which world-class scientists, philosophers, and Buddhist scholars develop a holistic approach to the scientific exploration of reality, but also adds scientific background to their presentations, as well as supplementary discussions with prominent participants and attendees. Interviews with His Holiness the Karmapa, the Buddhist monk Matthieu Ricard, and the actor and longtime human rights advocate Richard Gere take the proceedings into new directions, enriching the material with personal viewpoints and lively conversation about such topics as the origin of matter, the properties of cells, the nature of evolution, the ethics of genetic manipulation, and the question of consciousness and ethics. A keen study of character, Luisi incorporates his own amusing observations into this fascinating dialogue, painting a very human portrait of some of our greatest and most intimidating thinkers. Deeply textured and cleverly crafted, Mind and Life is an excellent opportunity for any reader to join in the debate surrounding this cutting-edge field of inquiry.

Methods, Models, Simulations and Approaches Towards a General Theory of Change - Proceedings of the Fifth National Conference on Systems Science

Author: Gianfranco Minati,Mario Abram,Eliano Pessa

Publisher: World Scientific

ISBN: 9814383325

Category: Computers

Page: 704

View: 6374

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The book contains the Proceedings of the 2010 Conference of the Italian Systems Society, see also Papers will deal with the interdisciplinary study of processes of changing related to a wide variety of specific aspects. Attempts to deal with them, based on generalising approaches used to study the movement of bodies and environmental influence, have included ineffective reductionistic simplifications. Indeed changing also relates, for instance, to processes of acquisition and varying properties such as for software; growing and aging biological systems; learning/cognitive systems; and socio-economic systems growing and developing through innovations. The aim of the book is to present very advanced studies and the generalisation of processes of changing as for processes of emergence. Papers in the book study the problem considering its transdisciplinary nature, i.e., systemic properties studied per se and not within specific disciplinary contexts. The aim of these studies is to outline a transdisciplinary theory of changes in systemic properties. Such a theory should have simultaneous, corresponding and eventually hierarchical disciplinary aspects as expected for a general theory of emergence. Within this transdisciplinary context, specific disciplinary research activities and results are assumed to be mutually represented as within a philosophical and conceptual framework based on the theoretical centrality of the observer. Models and theories will be based on the conceptual inseparability between observer and observer as in constructivism and for logically open systems. Contributions will deal such issues in interdisciplinary ways considering theoretical aspects and applications from Physics, Cognitive Science, Biology, Artificial Intelligence, Economics, Architecture, Philosophy, Music and Social Systems. Opening lecture “Criticality of Criticality in Causal Networks: Information transfer, storage and further issues” by Stuart Kauffman is found at

Beyond Mechanism

Putting Life Back Into Biology

Author: Brian G. Henning,Adam Christian Scarfe

Publisher: Rowman & Littlefield

ISBN: 0739174363

Category: Philosophy

Page: 474

View: 6630

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Pairing scientists and philosophers together, this book is an exploration of some of the new frontiers in biology (e.g., Emergence, Complex Systems, Biosemiotics, Symbiogenesis, Organic Selection, Epigenetics, Niche Construction, Teleodynamics, etc.). The chapters in this volume challenge the mechanistic metaphysic that is implicit in the reigning neo-Darwinist paradigm, point to more inclusive modes of thinking in relation to the nature of life, and contribute to the novel synthesis that is presently “in the air.”

Das fünfte Wunder

Auf der Suche nach dem Ursprung des Lebens

Author: Paul Davies

Publisher: S. Fischer Verlag

ISBN: 3105607579

Category: Self-Help

Page: 320

View: 8537

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Paul Davies gibt einen genauen und abwägenden Überblick über die vorhandenen Modelle der Entstehung des Lebens und fügt eine weitere, gut belegte Hypothese hinzu, nämlich die der Lebensentstehung fern von der Erde. (Dieser Text bezieht sich auf eine frühere Ausgabe.)

Comets and the Origin and Evolution of Life

Author: Paul J. Thomas,Roland D. Hicks,Christopher F. Chyba,Christopher P. McKay

Publisher: Springer Science & Business Media

ISBN: 3540330887

Category: Science

Page: 346

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This volume considers the role comets may have played in the origins and evolution of life. This is the only book dealing in depth with this subject. It is particularly relevant in light of recent investigations of Halley's comet, of new insights into organic synthesis in meteorites and comets, and of new results of numerical simulations of cometary orbits and impacts on Earth. The book is intended as a comprehensive review of current research.

A Companion to the Philosophy of Biology

Author: Sahotra Sarkar,Anya Plutynski

Publisher: Wiley-Blackwell


Category: Science

Page: 616

View: 3755

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Comprised of essays by top scholars in the field, this volume offers detailed overviews of philosophical issues raised by biology. Brings together a team of eminent scholars to explore the philosophical issues raised by biology Addresses traditional and emerging topics, spanning molecular biology and genetics, evolution, developmental biology, immunology, ecology, mind and behaviour, neuroscience, and experimentation Begins with a thorough introduction to the field Goes beyond previous treatments that focused only on evolution to give equal attention to other areas, such as molecular and developmental biology Represents both an authoritative guide to philosophy of biology, and an accessible reference work for anyone seeking to learn about this rapidly-changing field

Moleküle aus dem All?

Author: Katharina Al-Shamery

Publisher: John Wiley & Sons

ISBN: 3527637079

Category: Technology & Engineering

Page: 332

View: 7936

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Spannend wie ein Krimi: Big-Bang und Leben auf dem Mars Wie kam es dazu, dass sich unsere Erde allmählich aus dem Nebel des Sonnensystems zu formen begann und was ist dran an der Theorie, dass das Leben in Form von Sporen direkt aus dem All zu uns auf die Erde transportiert wurde? Unsere bisherige Evolutionsgeschichte liest sich schon spannend wie ein Krimi. Und hier verraten international renommierte Wissenschaftler auch ihre Zukunftsvisionen, wie z. B. Professor Jesco von Puttkamer (ISS und NASA), der ergründet, ob Leben auf dem Mars möglich ist. Wie nahrhaft war die Ursuppe? Ist das Leben aus einer üppigen und vor Nährstoffen strotzenden Ursuppe entstanden, warum ist es so schwer, den Molekülbaukasten der Erde zu erforschen und kennen Sie schon das älteste überlebende Urzeitrelikt? Hier bekommen Sie alle Antworten, die die Wissenschaft bislang erforscht hat, und machen sich mit Experten auf Spurensuche - unter anderem nach dem Stoff, aus dem die Gene sind. Wo sind sie alle? Auf der Suche nach außerirdischem Leben ”Die Erde als die einzige bevölkerte Welt im All anzusehen, ist ebenso absurd wie die Behauptung, auf einem mit Hirse gesäten Feld sprieße nur ein einziges Korn.“ Das schrieb ein Gelehrter im 4. Jahrhundert vor Christus. Doch auch heute noch steckt die Wissenschaft beim Erforschen außerirdischen Lebens in den Kinderschuhen und fragt sich: wo sind sie alle? Vor noch nicht langer Zeit wurde bestätigt, dass es außerhalb unseres Sonnensystems andere Welten gibt. Aber gibt es dort intelligente ”Nachbarn“? Und wie können die Menschen mit ihnen Kontakt aufnehmen? Die Wissenschaft arbeitet mit Nachdruck daran - und erzählt in diesem Buch, wie weit sie bisher gekommen ist.

Environmental Evolution

Effects of the Origin and Evolution of Life on Planet Earth

Author: Lynn Margulis,Clifford Matthews,Aaron Haselton

Publisher: MIT Press

ISBN: 9780262631976

Category: Science

Page: 338

View: 6671

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Fifteen distinguished scientists discuss the effects of life—past and present—on planet Earth.


eine philosophische Untersuchung

Author: Andreas Brenner,Ariane Willemsen,Eidgenössische Ethikkommission für die Biotechnologie im Ausserhumanbereich,Switzerland. Bundesamt für Bauten und Logistik

Publisher: N.A


Category: Biotechnology

Page: 192

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Creating Life in the Lab

How New Discoveries in Synthetic Biology Make a Case for the Creator

Author: Fazale Rana

Publisher: Baker Books

ISBN: 9781441214584

Category: Religion

Page: 240

View: 2890

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Each year brings to light new scientific discoveries that have the power to either test our faith or strengthen it--most recently the news that scientists have created artificial life forms in the laboratory. If humans can create life, what does that mean for the creation story found in Scripture? Biochemist and Christian apologist Fazale Rana, for one, isn't worried. In Creating Life in the Lab, he details the fascinating quest for synthetic life and argues convincingly that when scientists succeed in creating life in the lab, they will unwittingly undermine the evolutionary explanation for the origin of life, demonstrating instead that undirected chemical processes cannot produce a living entity.

Life's Solution

Inevitable Humans in a Lonely Universe

Author: Simon Conway Morris

Publisher: Cambridge University Press

ISBN: 9780521827041

Category: Science

Page: 464

View: 5051

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Contends that randomness in the universe is limited by the rules of physics and chemistry, resulting in repeated examples of evolutionary convergence that demonstrate life's ability to arrive at a single solution in different ways.